{"id":2318,"date":"2025-11-11T14:50:14","date_gmt":"2025-11-11T14:50:14","guid":{"rendered":"https:\/\/www.otizmvebilim.com\/?p=2318"},"modified":"2025-12-07T18:26:09","modified_gmt":"2025-12-07T18:26:09","slug":"otizm-ve-toxoplasma-paraziti-baglantisini-inceleyen-bir-arastirma","status":"publish","type":"post","link":"https:\/\/www.otizmvebilim.com\/?p=2318","title":{"rendered":"Otizm ve Toxoplasma Paraziti Ba\u011flant\u0131s\u0131n\u0131 \u0130nceleyen Bir Ara\u015ft\u0131rma"},"content":{"rendered":"

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MAKALEN\u0130N KISA \u00d6ZET\u0130<\/strong><\/p>\n

\u0130nceledi\u011fimiz 2022 y\u0131l\u0131 makalesinin ad\u0131: “Prevalence of the Parasite Toxoplasma Gondii in Autistic Children in Iraq”<\/span><\/p>\n

Bu ara\u015ft\u0131rmada Irak\u2019ta otizm tan\u0131s\u0131 alm\u0131\u015f \u00e7ocuklarda Toxoplasma gondii adl\u0131 parazitin g\u00f6r\u00fclme oran\u0131 incelenmi\u015ftir.Bu parazit genellikle kedi d\u0131\u015fk\u0131s\u0131, kirli su ya da iyi pi\u015fmemi\u015f et yoluyla bula\u015fabilmektedir. Ara\u015ft\u0131rmac\u0131lar, 30 otizmli \u00e7ocuk ile 15 sa\u011fl\u0131kl\u0131 \u00e7ocuk \u00fczerinde testler yapm\u0131\u015flard\u0131r.<\/span><\/p>\n

Sonu\u00e7lara g\u00f6re, otizmli \u00e7ocuklar\u0131n %13,3\u2019\u00fcnde parazite kar\u015f\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131 (IgG antikoru) bulunmu\u015ftur. Bu oran sa\u011fl\u0131kl\u0131 \u00e7ocuklara g\u00f6re daha y\u00fcksek \u00e7\u0131km\u0131\u015ft\u0131r. Ayr\u0131ca baz\u0131 otizmli \u00e7ocuklarda yeni enfeksiyon g\u00f6stergesi olan IgM antikoru da tespit edilmi\u015ftir, fakat bu fark anlaml\u0131 bulunmam\u0131\u015ft\u0131r.<\/span><\/p>\n

Bu sonu\u00e7lar, T. gondii enfeksiyonunun \u00f6zellikle erken ya\u015fta ya da anne karn\u0131nda ge\u00e7irilen formlar\u0131n\u0131n sinir sistemi geli\u015fimini etkileyebilece\u011fini d\u00fc\u015f\u00fcnd\u00fcrmektedir. Ancak \u00e7al\u0131\u015fma, do\u011frudan \u201cparazit otizme neden olur\u201d dememektedir. Ara\u015ft\u0131rmac\u0131lar, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi tepkileri ve beyin iltihaplanmas\u0131 gibi dolayl\u0131 etkilerin olabilece\u011fini belirtmektedir.<\/span><\/p>\n

Makale, hijyenin \u00f6nemine \u00f6zellikle dikkat \u00e7ekmektedir. Hamile kad\u0131nlar ve k\u00fc\u00e7\u00fck \u00e7ocuklar i\u00e7in kedi kumu temizlerken eldiven kullanmak, meyve-sebzeleri iyi y\u0131kamak ve etleri iyice pi\u015firmek gibi basit \u00f6nlemlerle bula\u015f riski azalt\u0131labilir.<\/span><\/p>\n

Ara\u015ft\u0131rma k\u00fc\u00e7\u00fck bir grup \u00fczerinde yap\u0131lm\u0131\u015ft\u0131r; bu nedenle sonu\u00e7lar genelleme yapmak i\u00e7in yeterli de\u011fildir. Yine de elde edilen bulgular, otizmli \u00e7ocuklarda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi ve \u00e7evresel etkenler aras\u0131ndaki karma\u015f\u0131k ili\u015fkiyi anlamak a\u00e7\u0131s\u0131ndan de\u011ferli g\u00f6r\u00fclmektedir.<\/span><\/p>\n

Sonu\u00e7 olarak bu \u00e7al\u0131\u015fma, parazitik enfeksiyonlar\u0131n sinir geli\u015fimi \u00fczerindeki olas\u0131 etkilerine dikkat \u00e7ekmekte, ancak tedavi ya da kesin bir neden-sonu\u00e7 ili\u015fkisi sunmamaktad\u0131r. Daha b\u00fcy\u00fck ve kapsaml\u0131 ara\u015ft\u0131rmalar\u0131n yap\u0131lmas\u0131 gerekti\u011fi vurgulanmaktad\u0131r. <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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MAKALE HAKKINDA DETAYLI B\u0130LG\u0130<\/strong><\/p>\n

Otizm ve Toxoplasma Paraziti Ba\u011flant\u0131s\u0131n\u0131 \u0130nceleyen Bir Ara\u015ft\u0131rma<\/b>
\n<\/b>
\n<\/b>Irak\u2019ta y\u00fcr\u00fct\u00fclen bu \u00e7al\u0131\u015fmada, otizm tan\u0131l\u0131 \u00e7ocuklarda Toxoplasma gondii adl\u0131 parazitin g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131 ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Toxoplasma gondii, \u00f6zellikle kedilerin d\u0131\u015fk\u0131s\u0131nda, iyi pi\u015fmemi\u015f etlerde veya kirli suda bulunabilen tek h\u00fccreli bir parazittir. Enfeksiyon genellikle fark edilmeden ge\u00e7se de, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131f bireylerde ve hamilelerde ciddi sonu\u00e7lara yol <\/span>a\u00e7abilmektedir. Makaleye g\u00f6re bu parazitin sinir sistemi \u00fczerindeki etkileri uzun s\u00fcredir tart\u0131\u015f\u0131lmakta, baz\u0131 bilim insanlar\u0131 taraf\u0131ndan n\u00f6rolojik geli\u015fimle ilgili olas\u0131 bir ba\u011flant\u0131 olabilece\u011fi \u00f6ne s\u00fcr\u00fclmektedir.<\/span><\/p>\n

Ara\u015ft\u0131rmada, 30 otizmli \u00e7ocuk ile 15 sa\u011fl\u0131kl\u0131 \u00e7ocuk yer alm\u0131\u015ft\u0131r. Her iki gruptan al\u0131nan kan \u00f6rneklerinde T. gondii\u2019ye kar\u015f\u0131 olu\u015fan ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131, yani IgG ve IgM antikorlar\u0131 test edilmi\u015ftir. \u00c7al\u0131\u015fmaya g\u00f6re, otizmli \u00e7ocuklar\u0131n %13,3\u2019\u00fcnde IgG antikoru pozitif bulunmu\u015ftur. Bu durum, bu \u00e7ocuklar\u0131n ge\u00e7mi\u015fte parazite maruz kald\u0131\u011f\u0131n\u0131 g\u00f6stermektedir. Sa\u011fl\u0131kl\u0131 kontrol grubunda ise bu oran daha d\u00fc\u015f\u00fck saptanm\u0131\u015ft\u0131r. Yeni enfeksiyon g\u00f6stergesi olan IgM antikoru, otizmli \u00e7ocuklar\u0131n %3,33\u2019\u00fcnde pozitif \u00e7\u0131karken, kontrol grubunda tespit edilmemi\u015ftir.<\/span><\/p>\n

Makalede elde edilen bu veriler, otizmli \u00e7ocuklarda parazite kar\u015f\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131n\u0131n daha s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc d\u00fc\u015f\u00fcnd\u00fcrmektedir. Ancak \u00e7al\u0131\u015fmaya g\u00f6re bu sonu\u00e7lar, Toxoplasma gondii enfeksiyonunun do\u011frudan otizme neden oldu\u011funu kan\u0131tlamamaktad\u0131r. Ara\u015ft\u0131rmac\u0131lar, parazitin merkezi sinir sisteminde inflamasyona (iltihaplanmaya) yol a\u00e7abilece\u011fini, bunun da sinir h\u00fccreleri aras\u0131ndaki ileti\u015fimi etkileyebilece\u011fini belirtmektedir. Yine de bu s\u00fcre\u00e7lerin otizmle ili\u015fkisi hen\u00fcz kesin olarak a\u00e7\u0131kl\u0131\u011fa kavu\u015fmam\u0131\u015ft\u0131r.<\/span><\/p>\n

Ara\u015ft\u0131rmada \u00e7evresel ve hijyenik fakt\u00f6rlere de dikkat \u00e7ekilmi\u015ftir. T. gondii enfeksiyonunun \u00f6zellikle \u00e7ocuklarda ve hamilelerde \u00f6nlenmesi i\u00e7in, temel hijyen kurallar\u0131na uyulmas\u0131n\u0131n b\u00fcy\u00fck \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131 vurgulanmaktad\u0131r. Buna g\u00f6re, kedi kumu temizlerken eldiven kullanmak, meyve ve sebzeleri iyice y\u0131kamak, \u00e7i\u011f veya az pi\u015fmi\u015f et t\u00fcketmemek bula\u015f riskini \u00f6nemli \u00f6l\u00e7\u00fcde azaltmaktad\u0131r. \u00c7al\u0131\u015fmada ayr\u0131ca toplumda bu konuda fark\u0131ndal\u0131\u011f\u0131n art\u0131r\u0131lmas\u0131n\u0131n, hem genel sa\u011fl\u0131k hem de n\u00f6rogeli\u015fimsel risklerin azalt\u0131lmas\u0131 a\u00e7\u0131s\u0131ndan yararl\u0131 olabilece\u011fi belirtilmi\u015ftir.<\/span><\/p>\n

Makaleye g\u00f6re \u00f6rneklem b\u00fcy\u00fckl\u00fc\u011f\u00fc s\u0131n\u0131rl\u0131 oldu\u011fundan, sonu\u00e7lar genellenebilir d\u00fczeyde de\u011fildir. Ancak bu t\u00fcr \u00e7al\u0131\u015fmalar, otizmin yaln\u0131zca genetik de\u011fil, \u00e7evresel ve biyolojik fakt\u00f6rlerle de etkile\u015fim i\u00e7inde olabilece\u011fini g\u00f6stermesi a\u00e7\u0131s\u0131ndan \u00f6nemlidir. Ara\u015ft\u0131rmac\u0131lar, daha geni\u015f \u00f6rneklemlerle, farkl\u0131 b\u00f6lgelerde ve molek\u00fcler d\u00fczeyde yap\u0131lacak yeni ara\u015ft\u0131rmalar\u0131n bu ili\u015fkinin mekanizmalar\u0131n\u0131 daha iyi a\u00e7\u0131klayabilece\u011fini ifade etmektedir.<\/span><\/p>\n

Sonu\u00e7 olarak bu \u00e7al\u0131\u015fma, otizmli \u00e7ocuklarda Toxoplasma gondii enfeksiyonuna kar\u015f\u0131 antikorlar\u0131n daha s\u0131k g\u00f6r\u00fclebilece\u011fini g\u00f6stermi\u015ftir. Bu bulgu, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi ile n\u00f6rogeli\u015fimsel bozukluklar aras\u0131ndaki karma\u015f\u0131k ili\u015fkiye \u0131\u015f\u0131k tutmaktad\u0131r. Ancak makalede vurguland\u0131\u011f\u0131 gibi, bu yaln\u0131zca bir ili\u015fki g\u00f6zlemidir; do\u011frudan neden-sonu\u00e7 ba\u011flant\u0131s\u0131 kurmak i\u00e7in daha fazla bilimsel kan\u0131ta ihtiya\u00e7 vard\u0131r.<\/p>\n

<\/span>Genel olarak, \u00e7al\u0131\u015fmaya g\u00f6re bu t\u00fcr parazitik enfeksiyonlar, sinir geli\u015fimini dolayl\u0131 bi\u00e7imde etkileyebilecek \u00e7evresel fakt\u00f6rler aras\u0131nda de\u011ferlendirilmektedir. Bu nedenle, erken \u00e7ocukluk d\u00f6neminde hijyen ve g\u0131da g\u00fcvenli\u011fi konusunda al\u0131nacak \u00f6nlemler hem toplum sa\u011fl\u0131\u011f\u0131 hem de n\u00f6rogeli\u015fimsel risklerin azalt\u0131lmas\u0131 a\u00e7\u0131s\u0131ndan b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r.<\/span>
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MAKALEN\u0130N K\u00dcNYES\u0130<\/strong><\/p>\n

Prevalence of the Parasite Toxoplasma Gondii in Autistic Children in Iraq<\/strong>
\n<\/span>
\n<\/b>Received: 13 Jul 2022; Accepted: 16 Aug 2022; Published: 21 Aug 2022<\/span><\/p>\n

Makaleye a\u015fa\u011f\u0131daki linkten ula\u015fabilirsiniz:<\/strong>
\nhttps:\/\/www.scivisionpub.com\/articles\/prevalence-of-the-parasite-toxoplasma-gondii-in-autistic-children-in-iraq-2380.html
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Her t\u00fcrl\u00fc sorunuzu a\u015fa\u011f\u0131daki form veya Whatsapp (0541 742 6750)<\/a> yoluyla sorabilirsiniz.<\/div>\n

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